GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs9876781 | 1 | rs9311423 | chr3:48420308 | TREX1 | chr3:48501186-48509043:+ | -0.42 | -4.99 | 6.38E-6 | Longevity |
| UVM | cis | rs10935120 | 1 | rs934093 | chr3:134195885 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.01 | 3.68E-9 | Height |
| UVM | cis | rs11190604 | 1 | rs9419897 | chr10:102246125 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs9420782 | chr10:102235015 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs9420785 | chr10:102240451 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs9420797 | chr10:102331147 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs1930961 | 1 | rs9624834 | chr22:25846015 | CRYBB2 | chr22:25615612-25627836:+ | 1.25 | 5.04 | 5.39E-6 | Bipolar disorder with mood-incongruent psychosis |
| UVM | cis | rs1930961 | 1 | rs9624835 | chr22:25846021 | CRYBB2 | chr22:25615612-25627836:+ | 1.25 | 5.04 | 5.39E-6 | Bipolar disorder with mood-incongruent psychosis |
| UVM | cis | rs1930961 | 1 | rs9624836 | chr22:25846087 | CRYBB2 | chr22:25615612-25627836:+ | 1.25 | 5.04 | 5.39E-6 | Bipolar disorder with mood-incongruent psychosis |
| UVM | cis | rs968567 | 1 | rs968567 | chr11:61595564 | FADS2 | chr11:61583728-61634825:+ | 0.85 | 7.9 | 1.27E-10 | Blood metabolite levels;Rheumatoid arthritis;Glycerophospholipid levels |
| UVM | cis | rs979233 | 1 | rs979233 | chr5:42375243 | C5orf51 | chr5:41904470-41921737:+ | -0.45 | -5.41 | 1.41E-6 | Systemic lupus erythematosus |
| UVM | cis | rs10935120 | 1 | rs9809619 | chr3:134280948 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs9876781 | 1 | rs9809843 | chr3:48434398 | TREX1 | chr3:48501186-48509043:+ | -0.38 | -4.8 | 1.25E-5 | Longevity |
| UVM | cis | rs9876781 | 1 | rs9812647 | chr3:48448914 | TREX1 | chr3:48501186-48509043:+ | 0.47 | 5.06 | 5.07E-6 | Longevity |
| UVM | cis | rs10935120 | 1 | rs9813774 | chr3:134227100 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |